About

Sam De Brouwer is a deep-tech entrepreneur and AI executive.

Sam is co-founder and Chief Executive Officer of XY.AI Labs, which builds agentic AI for healthcare operations, with Lamara De Brouwer (Co-Founder & CTO), Scott Cressman (Chief Product Officer) and Geert Trooskens (Chief AI Officer). She co-founded TEDAI San Francisco and curated it until 2026.

Sam's career began in European technology in the 1990s. At Starlab, an interdisciplinary research lab, she was part of the early team. In 1996, under the name Samia Lounis, she co-founded Jobscape, one of Europe's first online employment platforms, which was acquired by StepStone.

From 2009 Sam directed TEDxBrussels, and was advocacy director for One Laptop Per Child Europe, raising funds to equip two million children.

In the United States Sam co-founded Scanadu, a consumer digital health company with a lab at NASA Ames Research Center, and then doc.ai, where she was Chief Operating Officer and later Chief Executive Officer. Sharecare acquired doc.ai in 2021, and she served as Sharecare's Chief Strategy Officer until 2025.

Patents

US 11998364 B2 — Image-based system and method for predicting physiological parameters. Granted June 2024, filed as Samia De Brouwer, with Walter De Brouwer and Apurv Mishra.
Continuation of US 11026634, filed after the Sharecare acquisition and assigned to Sharecare AI.

US 11026634 B2 — Image-based system and method for predicting physiological parameters. Granted June 2021, filed as Samia De Brouwer, with Walter De Brouwer and Apurv Mishra.
Convolutional neural network predicting physiological parameters from images.

Founded

XY.AI Labs · TEDAI San Francisco · doc.ai · Scanadu · Jobscape